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Though their exact mechanism is unclear, proposed actions include activating DNA repair pathways, stimulating adenosine A 2A receptors, and enhancing extracellular signal–regulated kinase/mitogen-activated protein kinase signaling, processes that boost collagen production and reduce tissue breakdown
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Exenatide is based on exendin-4, a peptide found in Gila monster saliva, whilst semaglutide is a modified version of human GLP-1